Development andevaluation of a 2D-contraction-assay witha gelatine substrate for human dermal fibroblasts

REM of gold particel-sputted specimen

Gelatine consists of several types of collagen. Is it therefore possible to replace collagen type I with gelatine as a substrate for cell-contraction assays?

Cells, such like fibroblasts contract during their cell migration by tightening the filaments of their actin-cytoskeleton. This can be measured.

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[Iris Hube, Linda Leicht, Larissa Walter - SS 2016]