The effect of periodical and mechanical stretching on cell morphology and proliferation of chondrocytes: a testing model

Stretched cells (EdU/DAPI)

The cartilage regeneration of knee joints is getting more important in medicine. A usual method to heal damaged cartilage is the application of chondrocyte transplants with autologous chondrocytes. This method demands a cultivation of chondrocytes in vitro. The cells proliferate in cartilage after a transplantation. In the natural environment of the cartilage the chondrocytes are exposed to mechanical forces.

The aim of this project is to create a testing model which shows the effect of periodical and mechanical stretching on cell morphology and proliferation.

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[Aylin Yurtseven, Vasiliki Rousidi, Berrin Canbaz - SS 2016]